Actifed

Actifed is a registered trademark for a combination antihistamine and nasal decongestant medication used for cold and allergy symptoms. Developed in 1958 by Burroughs Wellcome & Company (now part of GlaxoSmithKline), the product was later acquired by Pfizer, and was most recently sold by Johnson & Johnson. In the U.S., the formula was changed in 2006 due to a change in the legal environment; at the same time, distribution of the product was limited to certain stores. The United States Food and Drug Administration, FDA, lists Actifed as discontinued.
2006 U.S. formula change
The original formula for Actifed contained pseudoephedrine hydrochloride 60 mg as the nasal decongestant and triprolidine hydrochloride 2.5 mg as the antihistamine. However, in response to widespread laws requiring products containing pseudoephedrine to be kept behind the pharmacy counter, Pfizer changed Actifed's U.S. formula in late 2006 to contain chlorpheniramine maleate...